Authors：Xie Jia, Zhu Ruilin, Yang Liu DOI: 10.3760/cma.j.issn.2095-0160.2016.12.021 Published 2016-12-10 Cite as Chin J Exp Ophthalmol, 2016,34(12): 1145-1148. Abstract [Download PDF] [Read Full Text] As a critical self-protection mechanism to maintain the cellular homeostasis and functions, autophagy plays a significant role in growth, adaptation, tumor suppression, aging, innate and acquired […]
Tag: Autophagy
Mechanisms of photoreceptor cell death and potential treatment strategies in retinal detachment
Authors：Li Tong, Sun Xiaodong DOI: 10.3760/cma.j.issn.2095-0160.2016.12.020 Published 2016-12-10 Cite as Chin J Exp Ophthalmol, 2016,34(12): 1140-1144. Abstract [Download PDF] [Read Full Text] Retinal detachment(RD)is one of the most common sight-threatening retinal diseases.Visual acuity is not always restored after successful reattachment of the retina.Photoreceptor cell death has been thought to […]
Relationship between autophagy and retinal ganglion cells in animal models of glaucoma
Authors: Fu Shiya, Zhang Xu DOI: 10.3760/cma.j.issn.2095-0160.2017.02.018 Published 2017-02-10 Cite as Chin J Exp Ophthalmol, 2017,35(2): 180-183. Abstract [Download PDF] [Read Full Text] The main pathological feature of glaucoma is progressive loss of retinal ganglion cells (RGCs), and the damage mechanisms have not been elucidated.Autophagy is a […]
Apoptosis and autophagy of retinal ganglion cell-5 cells induced by hydrostatic pressure
Authors: Wang Yuping, Wang Jing, Yuan Yuanzhi DOI: 10.3760/cma.j.issn.2095-0160.2017.04.002 Published 2017-04-10 Cite as Chin J Exp Ophthalmol, 2017,35(4): 293-298. Abstract [Download PDF] [Read Full Text] Background Researches showed that the mitochondrial-mediated apoptosis and autophagy play an important role in the survival of retinal ganglion cells (RGCs) in glaucoma.However, […]
Research progress of miR-204 in the regulation of ophthalmic diseases
Authors: Xu Yanying, Mao Xinbang DOI: 10.3760/cma.j.issn.2095-0160.2017.08.020 Published 2017-08-10 Cite as Chin J Exp Ophthalmol, 2017,35(8): 761-763. Abstract [Download PDF] [Read Full Text] MicroRNAs (miRNAs) are endogenous short nucleotide non-coding RNAs which widely exist in eukaryotic organisms, involved in the body’s life process, including cell growth, differentiation, […]
Role of autophagy in angiogenesis of retinal vascular endothelial cells under hypoxia condition
Authors: Li Rong, Du Junhui, Yao Yang, Yu Zhaoxiang, Fan Zhuo, Chang Weiping DOI: 10.3760/cma.j.issn.2095-0160.2018.03.006 Published 2018-03-10 Cite as Chin J Exp Ophthalmol, 2018,36(3): 187-193. Abstract [Download PDF] [Read Full Text] Objective To study the role of autophagy in proliferation, migration and tube formation of retinal vascular endothelial cells (RVECs) under […]
The expression change of autophagy-related factors in lens epithelial cells of diabetic mice
Authors: Cheng Rong, Zhang Lu, Huang Yusen DOI: 10.3760/cma.j.issn.2095-0160.2018.06.005 Published 2018-06-10 Cite as Chin J Exp Ophthalmol, 2018,36(6): 424-428. Abstract [Download PDF] [Read Full Text] Objective To investigate the role of autophagy in the development of diabetic cataract by detecting the expression of autophagy-related […]
Establishment of apoptosis model in mouse cone cell line 661W cells and the primary research on protective effects of autophagy
Authors: Gao Wenna, Xie Jia, Du Jiantong, Zhu Ruilin, Yang Liu DOI: 10.3760/cma.j.issn.2095-0160.2018.09.003 Published 2018-09-10 Cite as Chin J Exp Ophthalmol, 2018,36(9): 666-675. Abstract [Download PDF] [Read Full Text] Objective To establish the apoptosis model in mouse cone cell line 661W cells and to investigate the viability of 661W cells […]
The role of autophagy and potential therapeutic effect of autophagy regulation in cornea diseases
Authors: Zou Xuexiang, Li Juan DOI: 10.3760/cma.j.issn.2095-0160.2019.02.011 Published 2019-02-10 Cite as Chin J Exp Ophthalmol, 2019,37(2): 129-133. Abstract [Download PDF] [Read Full Text] Autophagy is a metabolic process of lysosomal-mediated degradation of damaged proteins or aging organelles, which plays an important role in maintaining the stability of […]