Authors: Tian J, Li Genlin DOI: 10.3760/cma.j.issn.2095-0160.2017.01.004 Published 2017-01-10 Cite as Chin J Exp Ophthalmol, 2017,35(1): 17-21. Abstract [Download PDF] [Read Full Text] Background Retinal transplantation is a new approach to the treatment of retinal degeneration diseases, and how to avoid or reduce the immune rejection after […]
Tag: Apoptosis
Apoptosis and autophagy of retinal ganglion cell-5 cells induced by hydrostatic pressure
Authors: Wang Yuping, Wang Jing, Yuan Yuanzhi DOI: 10.3760/cma.j.issn.2095-0160.2017.04.002 Published 2017-04-10 Cite as Chin J Exp Ophthalmol, 2017,35(4): 293-298. Abstract [Download PDF] [Read Full Text] Background Researches showed that the mitochondrial-mediated apoptosis and autophagy play an important role in the survival of retinal ganglion cells (RGCs) in glaucoma.However, […]
The promoting effects of insulin-like growth factor 1 on the biological behaviour of human retinal vascular endothelial cells
Authors: Wang Mengjiao, Liu Gaoqin, Xu Jing, Li Dan, Lu Peirong DOI: 10.3760/cma.j.issn.2095-0160.2017.05.007 Published 2017-05-10 Cite as Chin J Exp Ophthalmol, 2017,35(5): 417-422. Abstract [Download PDF] [Read Full Text] Background The suppression of retinal angiogenesis is one of primary treatment targets for retinal vascular diseases, so seeking the intervention targets […]
Protective effect of rapamycin on hypoxia-injuried retinal ganglion cells and its mechanism
Authors: Ren Jing, Qin Bo, Zou Chang, He Jing, Liu Shenwen DOI: 10.3760/cma.j.issn.2095-0160.2017.05.004 Published 2017-05-10 Cite as Chin J Exp Ophthalmol, 2017,35(5): 404-409. Abstract [Download PDF] [Read Full Text] Background Studies showed that rapamycin (Rapa) plays a protective effect on central nervous system by improving the aging of human brain […]
Protective effects of tissue factor targeting peptide on human retinal pigment epithelial cell damage induced by blue light
Authors: Li Dandan, Zou Xiulan, Chen Jingxia, Xu Zhe, Yu Yongzhen, Zhou Wenjie, Wang Guanfeng, Rao Benqiang, Zou Yuping DOI: 10.3760/cma.j.issn.2095-0160.2017.07.006 Published 2017-07-10 Cite as Chin J Exp Ophthalmol, 2017,35(07): 603-609. Abstract [Download PDF] [Read Full Text] Background Light-induced retinal damage results in the damage of retinl pigment epithelial (RPE) cells and therefore affects […]
Photobiomodulation of light emitting diode irradiation on apoptosis of retinal neuronal cells induced by high-glucose
Authors: Zhang Limin, Zhang Fengjiu, Lin Anling, Peng Xiangdong, Yang Jianling, Yu Lingyan, Wang Haiming, Gao Shikai DOI: 10.3760/cma.j.issn.2095-0160.2017.07.004 Published 2017-07-10 Cite as Chin J Exp Ophthalmol, 2017,35(07): 591-596. Abstract [Download PDF] [Read Full Text] Background To study the pathogenesis and management of diabetic retinopathy (DR) has an important clinical significance.With the development […]
Neuroprotective effects of brimonidine on retinal ganglion cells induced by oxidative stress mitochondrial dysfunction
Authors: Wang Lu, Lin Binwu, Wang Yan, Pang Long DOI: 10.3760/cma.j.issn.2095-0160.2018.01.003 Published 2018-01-10 Cite as Chin J Exp Ophthalmol, 2018,36(1): 12-15. Abstract [Download PDF] [Read Full Text] Objective To explore whether brimonidine has a protective effect on retinal ganglion cells (RGCs) through improving mitochondrial function under the oxidative stress. […]
Regulation of Krüppel-like factor 6 via activating transcription factor 4 pathway to apoptosis of human lens epithelial cells
Authors: Tian Fang, Zhao Jinzhi, Teng He, Huang Liangyu, Liu Xun, Su Ruihong, Gao Meizi, Zhang Xiaomin, Li Xiaorong, Dong Lijie, Zhang Hong DOI: 10.3760/cma.j.issn.2095-0160.2018.03.005 Published 2018-03-10 Cite as Chin J Exp Ophthalmol, 2018,36(3): 181-186. Abstract [Download PDF] [Read Full Text] Objective To investigate the regulating effects of Krüppel-like factor 6 (KLF6) on the apoptosis of […]
Role of mitochondrial DNA in human retinal pigment epithelium cells apoptosis induced by blue light
Authors: Zhou Wenjie, Yu Yongzhen, Xu Zhe, Zou Xiulan, Li Dandan, Zou Yuping DOI: 10.3760/cma.j.issn.2095-0160.2018.04.008 Published 2018-04-10 Cite as Chin J Exp Ophthalmol, 2018,36(4): 267-272. Abstract [Download PDF] [Read Full Text] Objective To research the role of mitochondrial DNA mediate the cultured human retinal pigment epithelium (hRPE) cell apoptosis induced by […]
Protective effects of carnosic acid on retinal ganglion cells in acute ocular hypertension rats model
Authors: He Liye, Liang Liang, Zhu Mengnan, Xiao Changyi, Tu Xiaokun DOI: 10.3760/cma.j.issn.2095-0160.2018.04.005 Published 2018-04-10 Cite as Chin J Exp Ophthalmol, 2018,36(4): 254-258. Abstract [Download PDF] [Read Full Text] Objective To observe the protective effects of carnosic acid on retinal ganglion cells (RGCs) in acute ocular hypertension rats model. Methods […]