Authors: Tian Jingjing, Jia Zhiyang, Fan Fang DOI: 10.3760/cma.j.cn115989-20200326-00213 Published 2020-05-10 Cite as Chin J Exp Ophthalmol, 2020,38(05): 442-446. Abstract [View PDF] [Read Full Text] Glaucoma is a chronic neurodegenerative disease of the optic nerve accompanied by apoptosis of the retinal ganglion cells, atrophy and depression […]
Tag: Retinal ganglion cells
Inhibitory effect of small interfering RNA-TLR9 on high glucose-induced retinal ganglion cell apoptosis
Authors: Yang Huihui, Kan Quane, Yu Lu, Li Xuqing, Huang Aiguo, Yuan Huijuan DOI: 10.3760/cma.j.issn.2095-0160.2019.10.008 Published 2020-01-10 Cite as Chin J Exp Ophthalmol, 2020,38(01): 38-44. Abstract [View PDF] [Read Full Text] Objective To investigate the effect of Toll-like receptor 9 (TLR9) on high glucose-induced retinal ganglion […]
Protective effect of miR-30b on retinal ganglion cells against oxygen-glucose deprivation in vitro
Authors: Huang Chanjuan, Huo Yan, Chen Chen, Ai Liqianyu, Zhou Yuanguo, Ye Jian DOI: 10.3760/cma.j.issn.2095-0160.2016.05.004 Published 2016-05-10 Cite as Chin J Exp Ophthalmol, 2016,34(5): 396-401. Abstract [Download PDF] [Read Full Text] Background Retinal ganglion cell (RGCs) death following ischaemic insult is the major cause of a number […]
Current researches on effects of retinal neuroglial cells in glaucoma
Authors: Xue Bo, Ji Min, Guan Huaijin DOI: 10.3760/cma.j.issn.2095-0160.2016.07.016 Published 2016-07-10 Cite as Chin J Exp Ophthalmol, 2016,34(7): 649-653. Abstract [Download PDF] [Read Full Text] Glaucoma is a degenerative disease of the retina and the optic nerve.The apoptosis of retinal ganglion cells is the pathological basis […]
Evaluation of macular ganglion cell complex and peripheral retinal nerve fiber layer structural damage in early primary glaucomous eyes by 3D-OCT
Authors: Yan Yujie, Sun Xinquan, Chen Shu, Shi Aiqun, Wang Zhijun DOI: 10.3760/cma.j.issn.2095-0160.2016.08.016 Published 2016-08-10 Cite as Chin J Exp Ophthalmol, 2016,34(8): 739-743. Abstract [Download PDF] [Read Full Text] Background In previous study, peripheral retinal nerve fiber layer (RNFL) thickness is considered […]
Protective effect of heat shock protein 70 on glaucomatous optic nerve injury
Authors: Chen Di, Guo Wenyi DOI: 10.3760/cma.j.issn.2095-0160.2019.06.015 Published 2019-06-10 Cite as Chin J Exp Ophthalmol, 2019,37(6): 477-480. Abstract [View PDF] [Read Full Text] Glaucoma is characterized by progressive loss of vision, which is caused by degeneration of retinal ganglion cells (RGCs). Heat shock proteins (HSP), whose expression […]
Protective effects of intravitreal injection of nerve growth factor on retinal ganglion cells in early diabetic rats
Authors: Lyu Hang, Wang Qichang, Tang Luosheng DOI: 10.3760/cma.j.issn.2095-0160.2019.06.005 Published 2019-06-10 Cite as Chin J Exp Ophthalmol, 2019,37(6): 425-431. Abstract [View PDF] [Read Full Text] Objective To investigate the protective effect of intravitreal injection of nerve growth factor (NGF) on apoptosis of retinal ganglion cells (RGCs) in early […]
A comparative study on protective effect of optical nerve between crocin and erigeron breviscapus in chronic ocular hypertensive rats
Authors：Lyu Bochang, Xu Zhiguo, Chen Tao, Shi Juan, Yang Xinguang DOI: 10.3760/cma.j.issn.2095-0160.2016.11.007 Published 2016-11-10 Cite as Chin J Exp Ophthalmol, 2016,34(11): 990-996. Abstract [Download PDF] [Read Full Text] Background The primary cause of glaucomatous optic nerve damage is apoptosis of nerve cell and disorder of retinal circulation.Erigeron breviscapus is confirmed to have […]
The role of mitochondrial dynamics in retinal ganglion cells
Authors: Hu Xinxin, Dai Yi DOI: 10.3760/cma.j.issn.2095-0160.2017.01.016 Published 2017-01-10 Cite as Chin J Exp Ophthalmol, 2017,35(1): 74-78. Abstract [Download PDF] [Read Full Text] Mitochondrial dynamics refers to the constant fission, fusion, docking, transportation, and mitophagy of mitochondria within cells.These dynamic processes are not only critical to regulating […]
Protection of cannabinoid to retinal ganglion cells against oxygen-glucose deprivation damage
Authors: Shen Yumeng, Lin Zhongqiao, Liu Shiliang, Tian Kailin, Chen Yuanyuan, Shen Yin DOI: 10.3760/cma.j.issn.2095-0160.2017.01.003 Published 2017-01-10 Cite as Chin J Exp Ophthalmol, 2017,35(1): 10-16. Abstract [Download PDF] [Read Full Text] Background Acute retinal ischemia anoxic injury is common in eye disorders, such as acute glaucoma, central retinal artery occlusion and […]