Authors: Fu Shiya, Zhang Xu DOI: 10.3760/cma.j.issn.2095-0160.2017.02.018 Published 2017-02-10 Cite as Chin J Exp Ophthalmol, 2017,35(2): 180-183. Abstract [Download PDF] [Read Full Text] The main pathological feature of glaucoma is progressive loss of retinal ganglion cells (RGCs), and the damage mechanisms have not been elucidated.Autophagy is a […]
Tag: Retinal ganglion cells
Effects of Rho associated kinase inhibitors on glaucoma and current researches
Authors: Wang Chao, Yu Ling DOI: 10.3760/cma.j.issn.2095-0160.2017.04.019 Published 2017-04-10 Cite as Chin J Exp Ophthalmol, 2017,35(4): 381-384. Abstract [Download PDF] [Read Full Text] Glaucoma is one of the main causes of blindness in the world, resulting from a slow and progressive loss of retinal ganglion cells (RGCs) […]
Protective effect of rapamycin on hypoxia-injuried retinal ganglion cells and its mechanism
Authors: Ren Jing, Qin Bo, Zou Chang, He Jing, Liu Shenwen DOI: 10.3760/cma.j.issn.2095-0160.2017.05.004 Published 2017-05-10 Cite as Chin J Exp Ophthalmol, 2017,35(5): 404-409. Abstract [Download PDF] [Read Full Text] Background Studies showed that rapamycin (Rapa) plays a protective effect on central nervous system by improving the aging of human brain […]
Aggravation effects of JAK-STAT signaling pathway in retinal ischemia reperfusion injury
Authors: Yang Le, Shi Rui, Shen Jiaquan, Xue Yushun DOI: 10.3760/cma.j.issn.2095-0160.2017.08.004 Published 2017-08-10 Cite as Chin J Exp Ophthalmol, 2017,35(8): 690-694. Abstract [Download PDF] [Read Full Text] Background Retinal ischemia reperfusion injury (RIRI) is a common pathological process of many retinal vascular diseases with comprehensive pathogenesis mechanism.Researches showed that […]
Diagnostic value of thickness of macular ganglion cell complex and retinal nerve fiber layer measured by optical coherence tomography in patients with anterior ischemic optic neuropathy
Authors: Hu Liying, Li Zhiqing, Li Xiaorong DOI: 10.3760/cma.j.issn.2095-0160.2017.10.010 Published 2017-10-10 Cite as Chin J Exp Ophthalmol, 2017,35(10): 903-907. Abstract [Download PDF] [Read Full Text] Background Anterior ischemic optic neuropathy (AION) is a common eye disease, and early diagnosis is very important for reserving useful vision.Frequency-domain optical coherence […]
Neuroprotective effects of brimonidine on retinal ganglion cells induced by oxidative stress mitochondrial dysfunction
Authors: Wang Lu, Lin Binwu, Wang Yan, Pang Long DOI: 10.3760/cma.j.issn.2095-0160.2018.01.003 Published 2018-01-10 Cite as Chin J Exp Ophthalmol, 2018,36(1): 12-15. Abstract [Download PDF] [Read Full Text] Objective To explore whether brimonidine has a protective effect on retinal ganglion cells (RGCs) through improving mitochondrial function under the oxidative stress. […]
Neuroprotective effects of tianmagouteng decoction on retinal ganglion cells in optic nerve crush model
Authors: Li Yujie, Ma Ke, Zhang Haijuan, Wang Haiyan DOI: 10.3760/cma.j.issn.2095-0160.2018.02.004 Published 2018-02-10 Cite as Chin J Exp Ophthalmol, 2018,36(2): 91-95. Abstract [Download PDF] [Read Full Text] Objective To investigate the neuroprotective effect and antioxidation mechanism of tianmagouteng decoction on retinal ganglion cells (RGCs) in optic nerve crush model. […]
Protective effects of carnosic acid on retinal ganglion cells in acute ocular hypertension rats model
Authors: He Liye, Liang Liang, Zhu Mengnan, Xiao Changyi, Tu Xiaokun DOI: 10.3760/cma.j.issn.2095-0160.2018.04.005 Published 2018-04-10 Cite as Chin J Exp Ophthalmol, 2018,36(4): 254-258. Abstract [Download PDF] [Read Full Text] Objective To observe the protective effects of carnosic acid on retinal ganglion cells (RGCs) in acute ocular hypertension rats model. Methods […]
Changes of mitochondrial dynamics related genes expression in a glaucoma rat model
Authors: Hu Xinxin, Dai Yi, Sun Xinghuai DOI: 10.3760/cma.j.issn.2095-0160.2018.07.003 Published 2018-07-10 Cite as Chin J Exp Ophthalmol, 2018,36(7): 494-499. Abstract [Download PDF] [Read Full Text] Objective To investigate the ultrastructural changes of mitochondria and dynamic changes of mitochondrial dynamics related genes in chronic ocular hypertension rat models. Methods […]
Inhibitory effect of Sema3A on axonal growth of primary retinal ganglion cells in mice
Authors: Zhang Jieqiong, Yan Jun, Ye Jian DOI: 10.3760/cma.j.issn.2095-0160.2019.03.004 Published 2019-03-10 Cite as Chin J Exp Ophthalmol, 2019,37(3): 180-184. Abstract [Download PDF] [Read Full Text] Objective To investigate the effect of Semaphorin3A(Sema3A) on axon growth of primary retinal ganglion cells (RGCs) in mice. Methods C57/BL6 mice within 24 […]