Authors: Lu Cheng, Zhang Fengyan, Zhang Yuhang, Zhang Jiajuan DOI: 10.3760/cma.j.cn115989-20210427-00280 Published 2022-06-10 Cite asChin J Exp Ophthalmol, 2022, 40(6): 514-523. Abstract [View PDF] [Read Full Text] Objective To explore the inhibitory effect of long non-coding RNA (lncRNA) KCNQ1 overlapping transcript […]
Category: Experimental Science
Inhibition of lens epithelial cell migration using different square-edge intraocular lenses in an in vitro capsular bag model
Authors: Lian Feiyue, Li Yang, Jiang Lingfeng, Shen Haoyue, Zhao Jiangyue, Yan Xiaoxiao, Yu Jiaming, Qin Yu DOI: 10.3760/cma.j.cn115989-20200514-00346 Published 2022-05-10 Cite asChin J Exp Ophthalmol, 2022, 40(5): 395-402. Abstract [View PDF] [Read Full Text] Objective To establish an in vitro […]
Regulation of miR-155 in H2O2-induced oxidative stress in lens epithelial cells via targeting SIRT1
Authors: Niu Yantao, Zhang Li, Xie Wenfang DOI: 10.3760/cma.j.cn115989-20201104-00735 Published 2022-05-10 Cite asChin J Exp Ophthalmol, 2022, 40(5): 404-413. Abstract [View PDF] [Read Full Text] Objective To investigate the role of microRNA (miR)-155 in hydrogen peroxide (H2O2)-induced oxidative stress injury in lens epithelial cells (LECs) […]
Inhibitory effect of melatonin on pyroptosis of lens epithelium cells and its mechanism
Authors: Yang Xin, Liu Xuhui, Meng Jia, Fang Mengyuan, Zhang Fengyan DOI: 10.3760/cma.j.cn115989-20210516-00307 Published 2022-05-10 Cite asChin J Exp Ophthalmol, 2022, 40(5): 414-421. Abstract [View PDF] [Read Full Text] Objective To investigate the inhibitory effect of melatonin on pyroptosis of lens epithelium cells (HLECs) induced […]
Promoting effect of miR-15a on high glucose-induced oxidative stress in human lens epithelial cells and its mechanism
·Experimental Research· Promoting effect of miR-15a on high glucose-induced oxidative stress in human lens epithelial cells and its mechanism Nan Anchao, Nan Jianru, Liu Yadong, Liu Xiangling Department of Ophthalmology, the Second Affiliated Hospital of Zhengzhou University, Zhengzhou 450014, China Corresponding author: Nan Anchao, Email: nananchao0208@163.com Abstract […]
Inhibitory effect of CLC-2 chloride channel targeted blocking on fibrosis of human conjunctival fibroblasts
Authors: Wu Sharengaowa, Cui Renzhe, Lu Di, Ding Haoxuan, Sun Lixia DOI: 10.3760/cma.j.cn115989-20200609-00410 Published 2022-04-10 Cite asChin J Exp Ophthalmol, 2022, 40(4): 294-302. Abstract [View PDF] [Read Full Text] Objective To investigate the inhibitory effect of CLC-2 chloride channel targeted blocking on fibrosis of human […]
Specific expression of transmembrane protein 26 in retina and its association with primary open-angle glaucoma
•Experimental Research• Specific expression of transmembrane protein, TMEM26, in retinas and its association with primary open-angle glaucoma Yin Yi, Mao Yao, Yang Zhenglin, Huang Lulin School of Medicine, University of Electronic Science and Technology of China, Department of Medical Genetics, Sichuan Academy of Medical Sciences & Sichuan Provincial People’s Hospital, Sichuan Provincial Key Laboratory for […]
Inhibitory effect of necrostatin-1 on necroptosis of retinal ganglion cells in rats with acute ocular hypertension
Authors: Jing Yuanyuan, Ma Yi, Wang Kai, Liu Zhuqing DOI: 10.3760/cma.j.cn115989-20191108-00488 Published 2022-04-10 Cite asChin J Exp Ophthalmol, 2022, 40(4): 310-315. Abstract [View PDF] [Read Full Text] Objective To investigate the inhibitory effect of specific inhibitor of necroptosis necrostatin-1 (Nec-1) on […]
Inhibitory effect of ILK-siRNA-AAV on scar formation after glaucoma filtering surgery in rats
Authors: Xing Yao, Wang Jianming, Fan Yazhi, Xiong Lei, Wang Wenjing, Cui Lijun DOI: 10.3760/cma.j.cn115989-20210617-00362 Published 2022-04-10 Cite asChin J Exp Ophthalmol, 2022, 40(4): 316-325. Abstract [View PDF] [Read Full Text] Objective To investigate the role of integrin-linked kinase (ILK)-small interfering RNA (siRNA)-adeno-associated virus (AAV) […]
Promoting effect of conditioned medium of human bone mesenchymal stem cells on proliferation, adhesion and neuronal differentiation of immortalized human Müller cell line
Authors: Ge Lingling, Li Yijian, Li Qiyou, Gu Xianliang, Huang Xiaona, Tao Zui, Xu Haiwei DOI: 10.3760/cma.j.cn115989-20210702-00386 Published 2022-03-10 Cite asChin J Exp Ophthalmol, 2022, 40(3): 199-209. Abstract [View PDF] [Read Full Text] Objective To explore the effects of conditioned medium of human bone marrow […]