Category: Experimental Science

Differential expression analysis of circular RNA in human retinal vascular endothelial cells induced by high glucose

·Experimental Research· Differential expression analysis of circular RNA in human retinal vascular endothelial cells induced by high glucose Jia Yangxue1, Wang Zhiling2, Wei Yingying2, Zhu Kai2, Gu Yonghao2 1Department of Ophthalmology, Second Affiliated Hospital of Wannan Medical College, Wuhu 241000, China; 2Department of Ophthalmology, Provincial Hospital Affiliated to Anhui Medical University, Hefei 230001, China Corresponding […]

Protective effect of myricitrin on retinal microvascular endothelial cells induced by high glucose and its regulation mechanism

·Experimental Research· Protective effect of myricitrin on retinal microvascular endothelial cells induced by high glucose and its regulation mechanism Liu Qian, Liu Changgeng, Li Haijun, Dong Yangzeng, Zhang Ying Department of Ophthalmology, Henan Provincial People’s Hospital, People’ s Hospital of Zhengzhou University, Henan Eye Hospital, Henan Eye Institute, Zhengzhou 450003, China Corresponding author: Liu Qian, […]

Effects of different intensity of lighting on refractive development and form deprivation myopia in guinea pigs

Authors: Li Congying,  Gan Jiahe,  Wang Meijun,  Cao Beihe,  Huang Ying,  He Xi,  Hua Ziyu,  Sun Minghao,  Li Shiming DOI: 10.3760/cma.j.cn115989-20220228-00079 Published 2022-06-10 Cite asChin J Exp Ophthalmol, 2022, 40(6): 491-497. Abstract                              [View PDF]   [Read Full Text] Objective To investigate the […]

Inhibitory effect of siRNA-Pax6 on biological behavior and epithelial-mesenchymal transition of human lens epithelial cells

Authors: Zheng Yuxing,  Yang Xiaoxi,  Yi Guoguo,  Wu Shuduan,  Feng Zhizhen,  Xia Zhaoxia DOI: 10.3760/cma.j.cn115989-20210423-00272 Published 2022-06-10 Cite asChin J Exp Ophthalmol, 2022, 40(6): 499-506. Abstract                                       [View PDF]  [Read Full Text] Objective To explore the effect of […]

Inhibitory effects of NADPH oxidase 4 inhibitor on the epithelial-mesenchymal transition of human RPE cells induced by bevacizumab

Auhtors: Xie Chaohui,  Hao Xianghui,  Yang Lingling,  Xu Haifeng DOI: 10.3760/cma.j.cn115989-20210407-00234 Published 2022-06-10 Cite asChin J Exp Ophthalmol, 2022, 40(6): 507-513. Abstract                               [View PDF]  [Read Full Text] Objective To observe the influence of nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX) 4 […]

Inhibitory effect of siRNA-KCNQ1OT1 on human lens epithelial cell apoptosis by targeting miR-199a-5p

Authors: Lu Cheng,  Zhang Fengyan,  Zhang Yuhang,  Zhang Jiajuan DOI: 10.3760/cma.j.cn115989-20210427-00280 Published 2022-06-10 Cite asChin J Exp Ophthalmol, 2022, 40(6): 514-523. Abstract                              [View PDF]  [Read Full Text] Objective To explore the inhibitory effect of long non-coding RNA (lncRNA) KCNQ1 overlapping transcript […]

Inhibition of lens epithelial cell migration using different square-edge intraocular lenses in an in vitro capsular bag model

Authors: Lian Feiyue,  Li Yang,  Jiang Lingfeng,  Shen Haoyue,  Zhao Jiangyue,  Yan Xiaoxiao,  Yu Jiaming,  Qin Yu DOI: 10.3760/cma.j.cn115989-20200514-00346 Published 2022-05-10 Cite asChin J Exp Ophthalmol, 2022, 40(5): 395-402. Abstract                              [View PDF] [Read Full Text] Objective To establish an in vitro […]

Regulation of miR-155 in H2O2-induced oxidative stress in lens epithelial cells via targeting SIRT1

Authors: Niu Yantao,  Zhang Li,  Xie Wenfang DOI: 10.3760/cma.j.cn115989-20201104-00735 Published 2022-05-10 Cite asChin J Exp Ophthalmol, 2022, 40(5): 404-413. Abstract                              [View PDF] [Read Full Text] Objective To investigate the role of microRNA (miR)-155 in hydrogen peroxide (H2O2)-induced oxidative stress injury in lens epithelial cells (LECs) […]

Inhibitory effect of melatonin on pyroptosis of lens epithelium cells and its mechanism

Authors: Yang Xin,  Liu Xuhui,  Meng Jia,  Fang Mengyuan,  Zhang Fengyan DOI: 10.3760/cma.j.cn115989-20210516-00307 Published 2022-05-10 Cite asChin J Exp Ophthalmol, 2022, 40(5): 414-421. Abstract                              [View PDF] [Read Full Text] Objective To investigate the inhibitory effect of melatonin on pyroptosis of lens epithelium cells (HLECs) induced […]

Promoting effect of miR-15a on high glucose-induced oxidative stress in human lens epithelial cells and its mechanism

·Experimental Research· Promoting effect of miR-15a on high glucose-induced oxidative stress in human lens epithelial cells and its mechanism Nan Anchao, Nan Jianru, Liu Yadong, Liu Xiangling Department of Ophthalmology, the Second Affiliated Hospital of Zhengzhou University, Zhengzhou 450014, China Corresponding author: Nan Anchao, Email: nananchao0208@163.com Abstract                  […]